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Respiratory morbidity in young people surviving cancer: Population-based study of hospital admissions, treatment-related risk factors and subsequent mortality

International Journal of Cancer Jan 22, 2019

Smith L, et al. - Researchers undertook this population-based study to investigate respiratory hospital admissions in long-term survivors of cancers diagnosed in young people and identify specific respiratory morbidities, treatment-related risks, and their relationship to subsequent morbidity and mortality. They linked population-based cancer registrations in Yorkshire, England, diagnosed between 1990 and 2011 (aged 0–29 years), to inpatient Hospital Episode Statistics (HES) for admissions up to 2017. Findings revealed a significantly increased risk of respiratory complications among survivors of childhood and young adult cancer—even several decades after treatment. Risk of admission for all respiratory conditions and pneumonia was higher for those provided treatment with chemotherapy with known lung toxicity. Patients admitted for pneumonia displayed the highest subsequent mortality vs those admitted with other respiratory conditions.

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