Residential ambient benzene exposure in the United States and subsequent risk of hematologic malignancies
International Journal of Cancer Feb 15, 2019
Teras LR, et al. - Researchers assessed potential links between benzene exposure and risk of hematologic cancers for the general public by using US Environmental Protection Agency National Ambient Toxics Assessment (NATA) estimates of low-level ambient benzene. For exposure estimation, participants’ residential address was linked to the NATA benzene estimates for that census tract. A diagnosis of incident hematologic cancer was made between 1997 and 2013 for 2,595 of 115,996 American Cancer Society Cancer Prevention Study-II Nutrition cohort participants (52,554 men, 63,442 women). Findings highlighted a link between ambient benzene and risk of hematologic malignancies, especially MDS, T-cell lymphoma, and follicular lymphoma. They also found a positive association of ambient benzene with any hematologic malignancy and follicular lymphoma in men. For females only, no significant associations were observed, but there were suggestive links with MDS and T-cell lymphoma.
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