Stergiou GS, Bountzona I, Alamara C, et al. - Researchers sought to assess the reproducibility of office (OBP), ambulatory (ABP), and home blood pressure (HBP) measurements in children and adolescents, and their implications in diagnosing hypertension in clinical practice and in pediatric hypertension research. Participants in the study were apparently healthy children and adolescents referred for suspected hypertension. Measurements of 2-visit OBP, 7-day HBP, and 24-hour ABP were conducted twice, 1 to 6 months apart. Fifty-eight people (mean age, 13.0 ± 2.9 years, 60.3% boys) were analyzed. The reproducibility of 24-hour ABP and HBP were similar and superior to that of visit-2 OBP and awake or asleep ABP. Such data indicate that 24-hour ABP and 7-day HBP have equal reproducibility in children and adolescents, superior to OBP and daytime or asleep ABP. These results have important implications for the diagnosis of hypertension in children in clinical practice and in the design of pediatric hypertension clinical research trials.