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Repeat adrenal vein sampling in aldosteronism: reproducibility and interpretation of persistently discordant results

Journal of Clinical Endocrinology and Metabolism Dec 22, 2020

Kline GA, Leung AAC, Sam D, et al. - Researchers conducted the study for determining reproducibility of biochemical results and diagnostic lateralization in patients undergoing repeat adrenal vein sampling(AVS). Participants in the study were patients with confirmed PA undergoing repeat AVS due to concerns about technical success or discordant diagnostic results. Repeat AVS when an initial attempt failed was feasible and generally successful. There was a modest association between individual repeat adrenal aldosterone/cortisol ratios and lateralization indices when AVS was performed twice. Final lateralization diagnosis in all cases was similar. This shows that AVS in PA is an accurate and reproducible localizing test.

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