Kamerer AK, et al. - In this study, researchers examined the test–retest reliability of measures that may have been proposed to have the potential to relate suprathreshold hearing deficits to site(s)-of-lesion along the peripheral auditory system in humans. They examined adults with audiometric normal hearing on a battery of behavioral and physiologic measures. The battery included (1) thresholds in quiet (TIQ), (2) thresholds in noise (TIN), (3) frequency-modulation detection threshold, (4) word recognition in four listening conditions, (5) distortion-product otoacoustic emissions, (6) middle ear muscle reflex, (7) tone burst-elicited auditory brainstem response (tbABR), and (8) speech-evoked ABR. Over two visits separated by at least 1-week, they repeated data collection for each measure. For threshold-independent hearing disorders, the residuals of the correlation between the suprathreshold measures and TIQ serve as functional and quantitative proxies because they designate the portion of the raw measures that is not dependent on TIQ. They used using intraclass correlation to assess the reliability of the residual measures. Analysis suggests mixed reliability of residual measures, emphasizing to practice caution when selecting measures for diagnostic tests of threshold-independent hearing disorders. A reliable estimate of threshold-independent hearing disorders in humans may be acquired via quantifying hidden hearing loss as the variance in suprathreshold measures of auditory function that is not due to TIQ.