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Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis

BMC Urology Apr 29, 2020

Arroyo XAS, Freixedas FG, Quetglas JLB, et al. - This study was attempted to assess the association of the 3 different types of endoscopic calcifications of the renal papilla (Randall’s plaque, intratubular calcification, papillary crater) with the type of stone and urine analysis. A prospective study was performed analyze 41 patients (age range: 18 to 80 years) who received retrograde intrarenal surgery for renal lithiasis (mean stone size: 15.3 ± 7.2 mm). Researchers endoscopically classified the renal papilla injuries as Randall’s plaque, intratubular calcification, or papillary crater. The categorized calculi as uric acid, calcium oxalate monohydrate (COM; papillary and cavity), calcium oxalate dihydrate (COD), or calcium phosphate (CP). They conducted a 24 h urine analysis of calcium, oxalate, citrate, phosphate, and pH in all patients. They ascertained association of each type of papillary injury with type of stone and urine chemistry. They applied Fisher’s exact test and Student’s t-test to ascertain the significance of relationships, and a p value below 0.05 was considered significant. Association were found between the different types of papillary calcifications that were endoscopically detected with stone chemistry and urine analysis. They noted that COD and CP stones were correlated with endoscopic tubular calcifications and papillary craters. An association was found between hypercalciuria and tubular calcification, and hypocitraturia and Randall’s plaque.

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