Wang Y, Yao M, Zou M, et al. - Findings demonstrate positive association of serum lipids, including total cholesterol, non–high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol with the presence of carotid intraplaque neovascularization (IPN) in a Chinese high–stroke‐risk population.

• A community‐based cross‐sectional study including a total of 250 people with a high risk of stroke (mean age, 67.20±8.12 years; 66.4% men), to assess the value of a novel Doppler method, superb microvascular imaging, in correlating serum lipid profiles and evidence of IPN in a population with a high risk of stroke.

• In 96 participants (38.4%), presence of carotid plaque IPN was detected by superb microvascular imaging.

• Those exhibiting IPN were more likely to be current smokers (34.0% vs 46.9%), and their identified carotid plaques were much thicker (2.35±0.63 mm vs 2.75±0.80 mm).

• Even post-adjusting for low‐density lipoprotein cholesterol, there was a significant association of non–high‐density lipoprotein cholesterol (odds ratio, 2.62) with the presence of carotid plaque IPN.