Wang W, Yin J, Wang X, et al. - Whether serum inhibitory activity for IgE, assessed using enzyme-linked immunosorbent facilitated antigen binding, can serve as a biomarker for clinical efficacy for subcutaneous immunotherapy (SCIT) in Artemisia-sensitized allergic rhinitis (AR) patients, was investigated in this study. Participants included 19 AR patients who were examined and had received Artemisia-specific SCIT for more than 8 months (19.68 months on average, ranging from 9 to 33 months). Prior to as well as following the treatment, peripheral blood samples were obtained. Findings revealed a significant increase in serum inhibitory activity for IgE following SCIT, however, no correlation was identified between it and clinical improvements by statistics analysis. Therefore, further inquiry is required to clarify if serum inhibitory activity for IgE can serve as a biomarker of efficacy for SCIT or not.