Relationship between nailfold capillary morphology and retinal thickness and retinal vessel density in primary open‐angle and angle‐closure glaucoma
Acta Ophthalmologica Apr 09, 2020
Rong X, et al. - In this cross‐sectional study, researchers contrasted the morphological features of the nailfold capillaries in glaucoma patients with those in healthy individuals. They also explored the association of nailfold capillary morphology with retinal thickness and retinal vessel density in patients with primary open‐angle (POAG) and primary angle‐closure glaucoma (PACG). Participants in the study were 51 patients with normal‐tension glaucoma, 32 patients with hypertension glaucoma, 32 PACG patients and 61 healthy subjects. Excluded were patients with connective tissue diseases or taking anticoagulation or antiplatelet agents. Nailfold capillary morphological characteristics, including lower capillary density, greater tortuosity, more dilated capillaries > 50 μm and more avascular zones > 100 μm, were more common in patients with POAG and PACG than in control individuals. Nailfold capillary bed abnormalities have been found in both POAG and PACG patients. Nailfold capillary features, particularly microvascular density and degree of tortuosity, were significantly associated with ganglion cell complex thickness and radial peripapillary capillary density in patients with POAG but not in those with PACG.
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