Yan A, Issar T, Tummanapalli SS, et al. - In the present study, the researchers examined changes in corneal nerve morphology in T2D and established connections between in vivo corneal confocal microscopy and markers of peripheral nerve structure and function. Thet selected 57 candidates with T2D and 26 healthy controls of similar age and sex distribution. In addition, they enlisted a disease control group of 54 candidates with T1D. Using the Total Neuropathy Score, all participants were evaluated for distal symmetrical polyneuropathy. The data presented in this work showed significant changes in corneal nerves in T2D people. Reductions in measures of the corneal nerve correlated with increased severity of the neuropathy. Correlations have been identified between corneal confocal microscopy and markers of voltage-gated potassium channel function.