Relation of subacute kidney injury to mortality after transcatheter aortic valve implantation
The American Journal of Cardiology Dec 20, 2021
Cigarroa R, Shaqdan AW, Patel V, et al. - The association between subacute changes in kidney function at 30 days post-transcatheter aortic valve implantation (TAVI) and survival was investigated; findings highlighted that cases at high risk of adverse outcomes could be detected via renal function monitoring post-discharge.
This is a retrospective analysis of patients who underwent TAVI and survived beyond 30 days with baseline, in-hospital, and 30-day measures of renal function.
Of 492 patients included, estimated glomerular filtration rate (eGFR) worsened in 102 (22%), improved in 110 (22%), and remained unaltered in 280 (56%).
Post-statistical adjustment, worse survival was observed in relation to worsened eGFR at 30 days (hazard ratio vs unchanged eGFR 2.09), whereas improvement in renal function was not related to survival (hazard ratio vs unchanged eGFR 1.30).
Elevated mortality post-TAVI was observed in relation to worsened renal function at 30 days following TAVI.
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