Relation of sex and race to outcomes in patients undergoing percutaneous intervention with drug-eluting stents
American Journal of Cardiology Dec 23, 2018
Iantorno M, et al. - In this retrospective analysis of data prospectively collected over 13 years from patients undergoing percutaneous coronary intervention (PCI) at a large tertiary hospital in the US, researchers assessed the 1-year major cardiovascular events based on gender and race. Of a total of 12,050 patients who had PCI, from 2003 to 2016, for both stable disease and acute coronary syndrome, 1952 were black men, 6,013 white men, 1,619 black women, and 2,466 white women. The main focus was on major cardiovascular events at 1 year. Via proportional Cox hazard model analyses, outcomes were assessed after adjusting confounders (ie, age, body mass index, presentation with acute myocardial infarction, diabetes, smoking, history of coronary artery disease, family history of coronary artery disease, hyperlipidemia, hypertension, prior cardiovascular intervention, and chronic kidney disease). Findings showed 1.3 to 1.5 times more chances of experiencing major cardiovascular events in black men and women and white women than in white men. A significant race by gender interaction was observed.
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