Zhao L, Niu P, Zhao D, et al. - Researchers investigated regional treatment disparities as well as racial genes impact survival results in China and the US patients experiencing proximal gastric cancer (PGC). Participants were PGC patients defined as tumors with the epicenter located in cardia (C16.0) or fundus (C16.1). The cohort (n = 40973) was split into 4 racial groups: Chinese (n = 5179), Black (n = 2429), White (n = 31185), and Others (n = 2096). An independent link of racial factors with poor survival including Black ethnicity and White ethnicity was observed, after controlling for confounding variables, when compared with Chinese ethnicity in total PGC patients. Among PGC patients from two high-volume databases SEER and China National Cancer Center database, who were analyzed in this study, findings showed that survival outcomes differed across different regions or races. These survival disparities may be impacted by a number of factors (e.g., access to screening, quality of gastrectomy, neo/adjuvant therapy, and biological genes itself). A better knowledge of these differences could give rise to interventions that may aid to abolish these disparities.