Chalmers BP, Mayman DJ, Jerabek SA, et al. - This study was attempted to assess the impact of stricter state prescribing regulations on opioid consumption following total knee arthroplasty (TKA). A total of 165 opioid-naive patients were included who underwent primary unilateral TKA at a single institution with a standardized perioperative pain protocol were examined. Researchers obtained opioid consumption, quantity, and refill patterns for 6 weeks following surgery. According to the outcomes, the institution of state regulations intended at reducing the quantity and refills of postoperative opioids led patients to consume fewer opioids following TKA. Many individuals are prescribed more opioids than they need which elevates their consumption and can elevate the risk for diversion, addiction, and misuse.