Fountoulakis N, et al. - Considering their DIABRISK-SL trial that demonstrated a trimonthly pragmatic lifestyle modification (P-LSM), as compared with a 12-monthly LSM advice (C-LSM), as efficacious in significantly reducing the primary composite endpoint of predictors of cardio-metabolic disease [new-onset type 2 diabetes (T2DM), hypertension, impaired glucose tolerance, impaired fasting glycaemia and markers of cardio-renal disease] in urban participants aged below 40 years with risk factors for T2DM, researchers sought to report the results of post hoc analyses for those who were aged below 18 (n = 1,725) in three age groups, particularly of 6–10 years (P-LSM n = 77, C-LSM n = 59), 10–14 years (P-LSM n = 534, C-LSM n = 556) and 14–18 years (P-LSM n = 239, C-LSM n = 260). Results suggest that the incidence of predictors of T2DM and hypertension could be reduced among young South Asians aged between 10 and 18 years at risk of T2DM via implementing a pragmatic lifestyle modification program. There is a need for further studies in younger populations to evaluate the impact and feasibility of interventions to reduce the burden of T2DM and associated cardio-metabolic risk.