Iuliano L, et al. - Researchers examined eyes with idiopathic vitreomacular traction (VMT) (n=16) treated with intravitreal ocriplasmin injection, to determine the alterations in perfusion density and in the foveal avascular zone (FAZ) by using optical coherence tomography angiography. They also included controls consisted of sixteen healthy eyes. At baseline and at 1 month post-injection, they calculated macular perfusion density in 3 plexuses [superficial capillary plexus (SCP), deep capillary plexus, choriocapillaris]. Findings revealed comparable perfusion density in VMT eyes vs healthy controls, but a smaller FAZ was seen in eyes with VMT. Irrespective of anatomical success, an attenuated perfusion density in the SCP was evident after ocriplasmin injection. Following ocriplasmin injection, microvascular alterations were evident, which could be due to retinal traction release.