Kulac I, et al. - The correlation between phosphatase and tensin homolog deleted on chromosome 10 (PTEN) alterations with the recurrence and progression in non-invasive low-grade papillary urothelial carcinoma (NILGPUC) of the bladder was determined via immunohistochemistry. The frequent occurrence of tumor relapse in patients with reduced PTEN, but this variation was not statistically significant. In contrast, decreased PTEN expression correlated with a higher number of recurrences. Thus, PTEN hasa connection with the disease course in NILGPUC of the bladder.