Reduced fetal growth velocity precedes antepartum fetal death
Ultrasound in Obstetrics & Gynecology Jun 08, 2021
Pacora P, Romero R, Jung E, et al. - Researchers herein investigated whether antepartum fetal death is preceded by reduced fetal growth velocity. In addition, they determined the predictive value of fetal growth velocity for antepartum fetal death relative to a single fetal biometric measurement at the last available ultrasound scan prior to diagnosis of demise. Including 4,285 singleton pregnancies, a retrospective, longitudinal study was performed in African-American women who underwent at least two fetal ultrasound examinations between 14 and 32 weeks of gestation and delivered a liveborn neonate (controls; n = 4,262) or experienced antepartum fetal death (cases; n = 23). Per outcomes, small-for-gestational age (EFW < 10th percentile) was not diagnosed in 74% of antepartum fetal death cases at the last ultrasound examination when the fetuses were alive, hence, there is necessity for alternative approaches to improve detection of fetuses at risk of fetal death. The sensitivity for prediction of antepartum fetal death nearly doubled when longitudinal sonographic evaluation was conducted to determine growth velocity compared with a single EFW measurement at the last available ultrasound examination. However, suboptimal performance still remained.
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