Seppä VP, Paassilta M, Kivistö J, et al. - Researchers undertook this inquiry to evaluate expiratory variability index (EVI) for its discriminative capacity between healthy controls and young children with recurrent wheeze on-and-off controller medication. They also examined the link between EVI and parentally perceived obstructive symptoms (the requirement for bronchodilator). In addition, measurement success rate was also evaluated. Participants were 68 patients (aged 1.0-5.6) and 40 healthy controls (aged 1.0-5.9 years). A three-month inhaled corticosteroid (ICS) treatment because of recurrent obstructive bronchitis was prescribed to the patients. At the termination of the treatment (0W) and 2 (2W) and 4 (4W) weeks following ICS withdrawal, EVI was measured by using impedance pneumography at home. Patients vs controls were found to have lower EVI, and a further decrease in EVI was evident following controller medication withdrawal, particularly when parentally perceived wheeze symptoms were present. Measurement success rate was 94%. A significant potential of this technique was observed for routine lung function examination of wheezy young children.