Izumaru K, et al. - Researchers examined population-based autopsy samples from the Hisayama Study, to examine the pathologic link between lower estimated glomerular filtration rates (eGFRs) and the severity of left ventricular hypertrophy (LVH), given that cardiac remodeling, including LVH and myocardial fibrosis, develops with the progression of kidney disease. Pathology examinations were carried out to assess the thickness of the left ventricular wall, sizes of cardiac cells, and percentages of fibrosis. Findings revealed the association of reduced eGFR with cardiac hypertrophy and fibrosis of the left ventricle, cardiac cell enlargement, and cardiac fibrosis.