Grover S, et al. - In persons with HIV (PWH) with and without a history of AIDS-defining illness (ADI), differences in cancer stage and mortality rates were determined. Researchers analyzed PWH with anal, oropharynx, cervical, lung cancers, or Hodgkin lymphoma diagnoses from January 2000 to December 2009 in the North American AIDS Cohort Collaboration on Research and Design. Findings revealed higher mortality and poorer survival after lung cancer diagnosis among PWH with a history of ADI vs those without. The findings of increased mortality and decreased survival among those with ADI (vs without) were consistent for all other cancers, though not statistically significant. This suggests the necessity for more investigations into how HIV-related immune suppression impacts cancer outcomes.