Francis SR, et al. - Two thousand six hundred ninety one women of all ages diagnosed with FIGO stage I-II, any grade endometrial cancer from 2000 to 2016 who were treated with at least a hysterectomy were included in a study by the researchers in order to investigate the institutional experience and oncologic outcomes for salvage treatment for the recurrence of early-stage endometrial cancer patients. Salvage radiotherapy (RT) was the only factor that was observed to be associated with improved overall survival (OS) on MVA for women with vaginal-only recurrences whereas salvage surgery, salvage RT, and salvage chemotherapy were linked with the improved OS for women with pelvic recurrences. For women with early-stage endometrial cancer, failure rates were low. Improved OS in women with vaginal-only recurrences, in contrast to pelvic or distant recurrences, were noticed. Therefore, for the treatment of women with vaginal-only recurrences, salvage RT seemed to be a vital factor. Further, for women with pelvic recurrences, aggressive multimodality treatment could be useful.