Hurt CN, et al. - The authors performed a comparison of the recurrence rates after complete response to topical treatment with either cidofovir or imiquimod for vulval intraepithelial neoplasia (VIN) 3. In this study, compared to imiquimod, a trend towards the maintenance of longer response following treatment with cidofovir was observed. The drugs were similar in terms of low adverse event rates. Acceptable safety profile of both drugs was evident.