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Rectovaginal colonization with pathogenic Escherichia coli during pregnancy and neonatal outcomes

Infection and Drug Resistance Oct 04, 2019

Liu TH, Wang HP, Cho FN, et al. - Researchers examined 137 women from southern Taiwan with singleton pregnancies to determine the prevalence, antimicrobial susceptibility, and neonatal outcomes of pathogenic E. coli colonization in these women. Prospective screening during prenatal examination led to the identification of 35.8% of asymptomatic pregnant women who had pathogenic E. coli colonization in the rectovaginal region. This indicates a high prevalence of pathogenic E. coli colonization in these women. Significant morbidities, including hospitalization, hyperbilirubinemia, and gastrointestinal symptoms, were noted among neonates born to such mothers. Following Benjamini–Hochberg adjustment, maternal colonization with pathogenic E. coli at the rectoanal site was identified to be a risk factor for neonatal hyperbilirubinemia
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