Zhu E, Xie H, Gu C, et al. - This research was sought to confirm the clinicopathological characteristics and prognosis of lung adenocarcinoma (ADC) with a filigree pattern and to further evaluate the association between the filigree pattern and the classical micropapillary (MP) pattern. Researchers retrospectively examined the clinical and pathologic characteristics of 461 Chinese patients with completely resected ADC (stage I, 310; stage II, 44; stage III, 107). The results exhibited that the lymph node micrometastasis indicated poor survival in patients with ADC with the filigree pattern or classical MP pattern. The outcomes demonstrated that similar clinicopathologic features between patients with the filigree pattern and the classical MP pattern support the inclusion of the filigree pattern in the MP category. The findings revealed that the recognition of the filigree pattern could provide beneficial prognostic information, particularly for stage I ADC.