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Re-intervention rates after bioprosthetic pulmonary valve replacement in patients less than 30 years of age: A multi-center analysis

The Journal of Thoracic and Cardiovascular Surgery Sep 15, 2020

Baird CW, Chávez M, Sleeper LA, et al. - Researchers examined data from 1,278 patients < 30 years of age receiving pulmonary valve replacement (PVR) at 8 centers between 1996 and 2015, to determine the difference in time to as well as the predictors of re-intervention by valve type in surgical bioprosthetic PVR in these patients. Use of multiple valve types was reported, most commonly employed were: CE Perimount, 488 (38.2%), CE Magna/MagnaEase, 361 (28.2%) and Sorin Mitroflow 322 (25.2). The occurrence of re-intervention was reported in 12.7% and was most often because of pulmonary stenosis (68.8%), with most re-interventions happening in children (85.2%) and with smaller valve sizes. Lack of a concomitant tricuspid valve procedure and valve type were identified as the only independent risk factors for re-intervention following controlling for age and valve size; Sorin and St. Jude valves were found to be related to similar time to re-intervention, and deteriorated more rapidly as compared with other valve types. Findings showed re-intervention occurred in 8% of patients by 5 years in this large multi-center study. Essentially, re-intervention rates differed according to valve type, independent of age and valve size.

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