Johnson AL, et al. - In this study of 130 (92 were completed and 38 were discontinued for various reasons) randomized clinical trials (RCTs), researchers assessed the rate of discontinuation or nonpublication of RCTs including individuals with head and neck cancer. This goal was assessed by evaluating 3 domains: discontinuation of trial, nonpublication of trial data, and feasibility of contacting trial investigators of the aforementioned trials. Of RCTs in head and neck cancer, 29.2% were stopped and 40.2% of the trials completed were never published. The findings suggest that RCT guidance needs exist for head and neck cancer. Reporting of reasons for discontinuing the trial appears to be lacking, and the publishing rates for the trial were low. This study is relevant to many doctors and researchers since it identifies potential sources of decreased productivity and ethics in research.