Benger JR, Lazaroo MJ, Clout M, et al. - In the AIRWAYS-2 cluster randomized controlled trial, the i-gel supraglottic airway device (SGA) vs tracheal intubation (TI) was evaluated as the first advanced airway management (AAM) strategy employed by Emergency Medical Service clinicians (paramedics) managing adult patients with non-traumatic out-of-hospital cardiac arrest (OHCA). The two groups did not differ in the primary outcome of modified Rankin Scale (mRS) score at 30 days/hospital discharge. Researchers sought to report outcomes to 6 months. Randomization was performed of paramedics from four ambulance services in England 1:1 to use an i-gel SGA (759 paramedics) or TI (764 paramedics) as their initial approach to AAM. Survival to 30 days/hospital discharge was reported for 767/9296 (8.3%) enrolled patients; of these, 317 survivors (41.3%) consented and were followed-up to 6 months. Per outcomes, the TI and i-gel groups did not exhibit any statistically significant difference at 3 and 6 months. Hence, they conclude that the initially inscribed finding of no significant difference between groups at 30 days/hospital discharge remain sustained on extending the period of follow-up to 6 months.