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Randomized trial evaluating the effect of aged garlic extract with supplements vs placebo on adipose tissue surrogates for coronary atherosclerosis progression

Coronary Artery Disease May 07, 2018

Zeb I, et al. - Given that aged garlic extract (AGE) has been shown to reduce the progression of coronary atherosclerosis, researchers assessed the impact of AGE with supplements (AGE+S) on epicardial adipose tissue (EAT), pericardial adipose tissue (PAT), subcutaneous adipose tissue (SAT), and periaortic adipose tissue (PaAT). At 1 year, AGE+S vs placebo showed a significantly lower increase in EAT, PAT, PaAT, and SAT. AGE+S was found to be related to favorable impacts on attenuating the progression rate of adipose tissue volumes.

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