Cho H, et al. - In patients whose hepatitis B virus (HBV) was well controlled, researchers assessed the connection between nonalcoholic fatty liver disease (NAFLD) and the risk of hepatocellular carcinoma (HCC). This investigation involved consecutive patients with chronic hepatitis B (CHB) whose serum HBV DNA levels with antiviral treatment were continuously suppressed < 2000 IU/mL. Subjects with concomitant hepatitis C infection, autoimmune hepatitis, or excessive alcohol use were excluded. In patients with CHB in whom HBV was effectively suppressed by antivirals, NAFLD raised the risk of HCC. Thus, the investigators suggested that concurrent NAFLD should be suspected in patients with an incomplete biochemical response.