Gupta DR, et al. - Researchers determined how survival was influenced by racial disparities in socioeconomic factors, tumor features, and rates of surgical utilization in patients with esophageal cancer (EC) identified from the SEER (Surveillance, Epidemiology, and End Results) registry, including Hispanics and whites aged 18-65 years. Overall cases were 22,531. Significantly higher unadjusted mortality was observed among Hispanics with EC as well as among Hispanics with locoregional EC, compared with whites. County of residence income and prevalence of smoking, tumor grade, stage, and primary site, and surgical utilization were independently related to survival by race. A decreased survival rate in relation to a lower rate of surgery was evident among Hispanics with potentially resectable EC vs whites, even when adjusting for relevant socioeconomic and tumor factors. The patient barriers to surgical treatment and the systemic biases present in medical care must be addressed.