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Racial disparities in time to treatment initiation and outcomes for early stage anal squamous cell carcinoma

American Journal of Clinical Oncology Oct 28, 2020

Goksu SY, Ozer M, Kazmi SMA, et al. - Among Black and White patients undergoing definitive chemoradiation for early stage anal squamous cell cancer (ASCC), researchers compared time to treatment initiation and overall survival (OS) for any disparities by race. They used the National Cancer Database to select patients diagnosed with early stage (stage I-II) ASCC between 2004 and 2016 who were treated with chemoradiation. They used the χ2 test to compare clinical and treatment variables by race, and OS was evaluated through Cox regression with 1:1 nearest neighbor propensity score matching. There were 90.6% White individuals among 9,331 patients. Findings revealed a longer time to treatment initiation as well as worse OS in Black patients vs White patients with early stage ASCC managed with chemoradiation. Black race was associated with higher odds of >6 weeks of time to treatment initiation in multivariable analysis.

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