Maningding E, Dall'Era M, Trupin L, et al. - The retrospective California Lupus Surveillance Project (CLSP) data were applied to examine racial and ethnic differences in lupus manifestations and in the timing and risk of developing severe manifestations. Researchers retrospectively distinguished a sum of 724 patients with systemic lupus erythematosus (SLE). They estimated prevalence ratios of SLE manifestations applying Poisson regression models stratified by race/ethnicity and adjusted for gender, age at SLE diagnosis, and disease duration. After SLE diagnosis, they examined onset of severe SLE manifestations applying Kaplan‐Meier methods to analyze time‐to‐event and Cox proportional hazards regression models to calculate hazard ratios. Substantial differences were noted in the prevalence of several clinical SLE manifestations among racial/ethnic groups and discovered that African Americans, Asian/Pacific Islanders, and Hispanic patients are at elevated risk of developing several severe manifestations following a diagnosis of SLE.