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Quantitative evaluation of lipid layer thickness and blinking in children with allergic conjunctivitis

Graefe's Archive for Clinical and Experimental Ophthalmology May 21, 2021

Yang B, Wen K, Li J, et al. - Researchers conducted this case-control study to quantitatively assess the lipid layer thickness (LLT) and blinking in children with or without allergic conjunctivitis (AC) and to compare those between the different types of AC. Eighty-one children with symptomatic AC with an average age of 9.62 ± 2.67 years were recruited and subdivided according to the subtypes of AC, including seasonal/perennial allergic conjunctivitis group and vernal keratoconjunctivitis (VKC)/atopic keratoconjunctivitis (AKC) group. As a control group, 82 age-matched healthy children were enrolled. Pediatric AC patients had significantly thinner LLT, shorter tear breakup time, lower total blinking but higher partial blinking rate, particularly those with VKC/AKC. Reduced LLT and blinking disorders in pediatric AC patients may contribute to lipid layer deficiency in the long run, which should be considered and properly diagnosed for more precise treatment.

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