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Quantitative analysis of the choriocapillaris in uveitis using en face swept source optical coherence tomography angiography

American Journal of Ophthalmology May 15, 2020

Chu Z, Weinstein JE, Wang RK, et al. - In this retrospective cross-sectional study, researchers performed a quantitative analysis of choriocapillaris (CC) flow deficits (FDs) in individuals with uveitis. Swept-source optical coherence tomography based angiography macular volume scans (3x3 mm and 6x6 mm) were acquired utilizing the PLEX® Elite 9000: En face CC images were generated and analyzed using an automated flow deficit identification algorithm. Participants in the study were 38 controls (38 eyes) and 73 uveitis patients (73 eyes). There were no major variations between the quantitative metrics of controls and patients without choroidal involvement. Automated CC quantification can identify pathological FDs and provide quantitative metrics to describe these lesions in patients with uveitis. Patients suffering from posterior uveitis have significantly larger CC FDs than patients with other forms of uveitis.

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