Augustin M, et al. - This paper comprised of a comparative assessment of the feasibility and performance of three instruments estimating the health-related quality of life (HRQoL) in chronic ulcers: The Freiburg Life Quality Assessment for wounds (FLQA-w), the Cardiff Wound Impact Schedule (CWIS) and the Würzburg Wound Score (WWS). It was determined that the FLQA-w, the CWIS and the WWS were reliable, sensitive and valid tools for the HRQoL analysis in leg ulcers. Nevertheless, variations were exhibited in the clinical feasibility and patient acceptance.