Shah N, et al. - In this study, 2,299 patients with left ventricular ejection fraction < 35% were analyzed to assess the relationship between pulse pressure (PP) and mortality, cardiovascular (CV) mortality, stroke and heart failure hospitalizations (HFH). An association of the lowest tertile of PP (<42 mm Hg) with significantly higher CV mortality and HFH was seen. A decrease in CV death and HFH with greater PP, with adjusted hazard ratios of 0.91 and 0.93 per 10 mm Hg increase in PP, was seen via Cox proportional hazard models; this correlation was more distinct in those with New York Heart Association functional class III-IV. They found a low PP (<40 mm Hg) projected worse prognosis, while a high PP (>50 mm Hg) prognosticated a relatively favorable prognosis.