• Profile
Close

Pubertal growth and adult height in relation to breast cancer risk in African American women

International Journal of Cancer Sep 01, 2017

Bertrand KA et al. - In the current study, height was shown to be a strong risk factor for ER+ breast cancer in African American women. Early age at attained height was shown to be a risk factor for both ER+ and ER- breast cancer. Furthere, adult height and timing of pubertal growth were shown to be inter-related, but independent risk factors for breast cancer. 

Methods
The associations between adult height, age at attained height, and age at menarche with incidence of invasive breast cancer was determined in 55,687 African American women in the prospective Black Women's Health Study. 

Results
Over 20 years, 1,826 invasive breast cancers (1015 ER+ and 542 ER-) were accrued.
Adult height was associated with an increased risk of ER+ breast cancer (HR = 1.44 for height greater than or equal to 70 inches vs. less than or equal to 63 inches), but not ER- (HR = 1.16).
HRs for attained height before age 13 vs. age >17 were 1.30 for ER+ and 1.25 for ER- breast cancer.
Results for age at menarche (less than or equal to 11 years vs. greater than or equal to 14 years) were similar for ER+ and ER- breast cancer (HR for breast cancer overall = 1.30). 

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay