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Psychotropic drug use in community-dwelling people with young-onset dementia: Two-year course and determinants

Aging and Mental Health Nov 28, 2019

Gerritsen AAJ, Bakker C, Bruls E, et al. - People with young-onset dementia were examined for the course of psychotropic drug use. In addition, an exploration was performed regarding possible associations with age, gender, dementia severity, dementia subtype, and neuropsychiatric symptoms. Researchers studied data of 198 community-dwelling persons participating in the Needs in Young-onset Dementia study for their psychotropic drug use at baseline, as well as at 6, 12, 18 and 24 months and classified them into five groups (antiepileptics, antipsychotics, anxiolytics, hypnotics/sedatives and antidepressants) and quantified them as ‘present’ or ‘absent’. Findings suggest that despite the recommendations of various guidelines, the prevalence of psychotropic drug use has increased statistically significantly from 52.3% to 62.6% in community-dwelling people with young-onset dementia during the course of the study. They noted a positive association of increasing age with psychotropic drug use at baseline, while there was a negative association of apathy symptoms. Based on these findings, they recommend paying more attention to timely evaluate psychotropic drug use and encouraging the introduction of self-management programs for caregivers to support caregivers in dealing with the neuropsychiatric symptoms caused by dementia.
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