Brown MJ, et al. - Among adults aged 50 and older, researchers investigated how generalized anxiety disorder (GAD), posttraumatic stress disorder (PTSD), substance use disorders (SUD), and depression are associated with HIV diagnosis and how they differ by age, sex, and race/ethnicity. Analysis of data obtained from Cerner Corporation’s Health Facts ^® database revealed positive associations between SUD, depression, GAD, PTSD, and HIV. These associations were noted to differ by age, sex and race/ethnicity. There was a 10 times higher likelihood to have an HIV diagnosis in men who were diagnosed with GAD vs not diagnosed with GAD, after adjusting for age, race/ethnicity and marital status. They noted a five times higher likelihood of an HIV diagnosis among women who were diagnosed with GAD vs not diagnosed with GAD. They recommend addressing GAD, PTSD, SUD, and depression and considering age, sex and racial/ethnic disparities in implementing HIV prevention and intervention programs for older adults.