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Prospective association between adherence to the Mediterranean diet and hepatic steatosis: The Swiss CoLaus cohort study

BMJ Open Dec 26, 2020

Khalatbari-Soltani S, Marques-Vidal P, Imamura F, et al. - By performing this population-based prospective cohort study, researchers examined the prospective link between adherence to the Mediterranean diet and risk of developing hepatic steatosis. At first follow-up in 2009–2012, a total of 2,288 adults (65.4% women, aged 55.8±10.0 years) without hepatic steatosis were assessed. Following multivariable adjustment, a lower risk of hepatic steatosis based on Fatty Liver Index (FLI) was observed in relation to higher adherence to Mediterranean diet score (MDS). On applying non-alcoholic fatty liver disease (NAFLD) score, experts found no significant link between MDS and risk of hepatic steatosis. Considering the observed inverse link between adherence to the Mediterranean diet and incidence of hepatic steatosis based on the FLI, it was suggested that Mediterranean diet has a potential role in preventing hepatic steatosis. The necessity for precise population-level evaluation of fatty liver and its physiological markers is indicated by the noted inconsistency of this link when hepatic steatosis was evaluated using NAFLD score.

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