Jiang Y, et al. - Researchers conducted this investigation to determine the role of prosaposin (PSAP) in mesenchymal glioblastoma (GBM). In order to detect the expression of PSAP in different GBM subtypes, they used bioinformatic analysis, western blotting and RT-qPCR. Findings suggested that PSAP overexpression and secretion may be an important factor that causes high mesenchymal GBM invasiveness. Therefore, PSAP is a potential target for mesenchymal GBM treatment.