Rencuzogullari I, et al. - This study performed on patients who underwent primary percutaneous coronary intervention (pPCI) for ST segment elevation myocardial infarction (STEMI), aimed to assess the link between new-onset atrial fibrillation (NOAF) and coronary artery disease (CAD) severity using Syntax score (SS) and Syntax score II (SSII). This inquiry put forth the first comprehensive assessment of this link. Findings showed that in this patient population, high SSII was significantly associated with NOAF and independently predicted NOAF. Additionally, an association was obvious between NOAF and poor prognosis.

Methods

• This study included a total of 1,565 consecutive STEMI patients who were treated with pPCI.
• A comparison was performed between patients with NOAF and patients without NOAF in the entire study population and in a matched population defined by propensity score matching.

Results

• Findings demonstrated that patients with versus without NOAF had significantly higher SS and SSII, both in the matched population (18.6 ± 4 vs 16.75 ± 3.6; p < .001 and 42 ± 13.4 vs 35.1 ± 13.1; p < .001, respectively), and in all study population (18.6 ± 4 vs 16.5 ± 4.6; p < .001 and 42 ± 13.3 vs 31.5 ± 11.9;p < .001 respectively).
• Researchers found that SSII, compared to its components, was the only independent predictor of NOAF (OR: 1,041 95% CI: 1.015–1.068; p = .002).
• According to findings of long-term follow-up, patients with NOAF than those without NOAF had significantly higher all-cause long-term mortality (23.3% vs. 11%;p = .032).