Burg D, et al. – The target of this investigation was to screen the botanically derived molecules for FGF5 inhibitory activity in vitro and to evaluate the efficacy in a clinical setting. The results disclosed that isolates from the monoterpenoid family illustrated efficacy in FGF5 inhibition in vitro. A topical formulation comprising of a leading isolate notably improved anagen:telogen (AT) ratio, reduced hair fall and increased apparent hair density in the examine cohort of men and women.