Liu L, et al. - Researchers conducted this prospective cross-sectional study in order to detect plexus-specific peripapillary retinal perfusion defects in glaucoma using projection-resolved optical coherence tomography angiography (PR-OCTA). Using 4.5-mm OCTA scans centered on the disc, they scanned one eye each of 45 perimetric glaucoma participants and 37 age-matched normal participants. The glaucoma group displayed a more pronounced reduction in perfusion in superficial layers of the peripapillary retina [nerve fiber layer plexus (NFLP) and superficial vascular complex (SVC = NFLP + ganglion cell layer plexus)] than the deeper layers. Findings support the possible utility of reflectance-compensated capillary density and vessel density parameters for both NFLP and SVC in the clinical management of glaucoma.