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Progressive retinal nerve fibre layer thinning and choroidal microvasculature dropout at the location of disc haemorrhage in glaucoma

British Journal of Ophthalmology Jul 21, 2020

Kim CY, Lee EJ, Kim JA, et al. - This study was undertaken to determine if parapapillary choroidal microvasculature dropout (MvD) is correlated with progressive retinal nerve fibre layer (RNFL) thinning in eyes with primary open-angle glaucoma (POAG) and disc haemorrhage (DH). Parapapillary microvasculature was assessed by swept-source optical coherence tomography (OCT) angiography (OCTA) in 50 eyes with POAG and DH, 1 year before, at the time of and 1 year after the detection of DH. At 1 year after detection of DH, the cumulative prevalence of MvD was 76.0%. In eyes with POAG, RNFL thinning at MvD 's location was spatially consistent and progressive followed by subsequent DH and continued to progress after DH occurred. Progressive RNFL thinning was more likely to occur after the detection of DH when DH was not accompanied by MvD.

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