Krishnasamy R, et al. – The authors explored the available literature work regarding the progression of arterial stiffness in patients with chronic kidney disease (CKD). They illustrated that both arterial stiffness and serum fibroblast growth factor 23 (FGF23) were associated with increased cardiovascular risk in patients with CKD. Moreover, they also reported a significant association between serum FGF23 and arterial calcification and stiffness. Thus, more likewise studies were required to evaluate the temporal relationship as well as the pathological mechanisms linking FGF23 and vascular disease.