Wang J, Li Y, Musch DC, et al. - Researchers conducted this prospective cross-sectional study to examine the refractive changes and prevalence of myopia in school-aged children during the coronavirus disease 2019 (COVID-19) home confinement. Using a photoscreener device, noncycloplegic photorefraction was examined. Of the 123,535 children involved in the research, 64,335 (52.1%) were boys. In total, 194,904 test results (389,808 eyes) were involved in the analysis. According to 2020 school-based photoscreenings, home confinement during the COVID-19 pandemic tended to be correlated with a significant myopic shift for children aged 6 to 8 years. In the interpretation of these associations, however, numerous limitations warrant caution, including use of noncycloplegic refractions and absence of orthokeratology history or ocular biometry data. The refractive status of younger children may be more sensitive to environmental changes than of older ages, given that younger children are in a critical period for myopia development.