• Profile
Close

Prognostic value of multiparametric magnetic resonance imaging, transient elastography and blood‐based fibrosis markers in patients with chronic liver disease

Liver International Dec 04, 2020

Jayaswal ANA, Levick C, Selvaraj EA, et al. - As liver cT1, liver T1, transient elastography (TE) and blood‐based biomarkers have independently been shown to effectively predict clinical outcomes, researchers utilized a cohort of 197 patients with compensated chronic liver disease to compare their prognostic value. Participants were 61% male, had a median age of 54 years, and were were followed up for 693 patient‐years (median 43 (26‐58) months). This study’s findings demonstrate that clinical outcomes can be predicted by liver cT1, TE, and serum‐based biomarkers, but when taking into account technical failure/unreliability, TE cut‐offs perform worse than those of cT1 and blood biomarkers. NAFLD (41%), viral hepatitis (VH, 25%) and alcohol‐related liver disease (ArLD; 14%) were the most commonly diagnosed conditions. Clinical outcomes were predicted by liver cT1 > 825ms with HR 9.9, TE > 8kPa with HR 7.8 and FIB‐4 > 1.45 with HR 4.09. Liver cT1 > 825 ms could predict clinical outcomes, but TE > 8kPa could not, after analysis taking into account technical failure and unreliability.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay