Lee CS, Hong B, Kasi SK, et al. - In this prospective cohort study, involving 50 patients (mean age 72 years old; 52% male), researchers sought to associate the detection of potential pathogen DNA in endophthalmitis with clinical outcomes. The sample consisted of patients in whom endophthalmitis was diagnosed following an intraocular procedure. Clinical outcome data from baseline, week-1, month-1, and month-3 visits have been obtained. It was noted that 24 cases were culture-positive and 26 were culture-negative. The presence of torque teno virus (TTV) at presentation was linked to a higher rate of secondary pars plana vitrectomy and retinal detachment. In post-procedure endophthalmitis, the presence and higher load of bacteria other than S epidermidis detected by WGS or DNA from TTV by a quantitative polymerase chain reaction in ocular fluids is associated with worse results.